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. 2000 Feb;82(3):535-7.
doi: 10.1054/bjoc.1999.0959.

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

M Palicio  1 , I Blanco, S Tórtola, I González, E Marcuello, J Brunet, F Lluis, J J González-Aguilera, M A Peinado, G Capella
Affiliations

Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

M Palicio et al. Br J Cancer. 2000 Feb.

Abstract

A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function.

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