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Review
. 2000 Feb;105(4):409-11.
doi: 10.1172/JCI9459.

Gene silencing as a threat to the success of gene therapy

Affiliations
Review

Gene silencing as a threat to the success of gene therapy

T H Bestor. J Clin Invest. 2000 Feb.
No abstract available

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References

    1. Bestor TH, Chandler VL, Feinberg AP. Epigenetic effects in eukaryotic gene expression. Dev Genet. 1994; 15:458–462. - PubMed
    1. Yoder JA, Walsh CP, Bestor TH. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 1997; 13:335–340. - PubMed
    1. Berleth T, Nobis P, Jaenisch R, Harbers K. Activation of endogenous retroviral genomes in Mov strains of mice. J Gen Virol. 1987; 68:2919–2923. - PubMed
    1. Bestor TH, Tycko B. Creation of genomic methylation patterns. Nat Genet. 1996; 12:363–367. - PubMed
    1. Wolffe AP, Matzke MA. Epigenetics: regulation through repression. Science. 1999; 286:481–486. - PubMed

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