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Review
. 1999 Dec;48(6):581-4.
doi: 10.1080/713803577.

Hypothetical double-helical poly(A) formation in a cell and its possible biological significance

M I Zarudnaya  1 , D M Hovorun
Affiliations
Free article
Review

Hypothetical double-helical poly(A) formation in a cell and its possible biological significance

M I Zarudnaya et al. IUBMB Life. 1999 Dec.
Free article

Abstract

Arguments are presented in favor of capability of poly(A)-tracts of cellular RNA to form double helices in vivo. It is suggested that formation of the double helix in the mRNA poly(A) tall provides the basis for such processes as polyadenylation termination, PAB I synthesis autoregulation, and stabilization of ARE-containing mRNA by ELAV-like proteins.

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