Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses
- PMID: 1068460
- PMCID: PMC431140
- DOI: 10.1073/pnas.73.10.3484
Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses
Abstract
Examination of old human lenses indicates that low-molecular-weight alpha crystallin is not present in the inner 30-40%, the nucleus, of the lens. The remainder of such lenses, the periphery, contains normal levels of this protein. This finding is in marked contrast to observations in young lenses, where a large quantity of this protein is found throughout the tissue.
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