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. 2000;26(2):215-22.
doi: 10.1002/(sici)1096-9101(2000)26:2<215::aid-lsm13>3.0.co;2-o.

Deep coagulation of dermal collagen with repetitive Er:YAG laser irradiation

B Majaron  1 , S M Srinivas, H e Huang, J S Nelson
Affiliations

Deep coagulation of dermal collagen with repetitive Er:YAG laser irradiation

B Majaron et al. Lasers Surg Med. 2000.

Abstract

Background and objective: Er:YAG lasers are known to effectively ablate human skin with minimal thermal damage to subjacent dermal tissue. We have investigated whether deep coagulation of dermal collagen, similar to that observed with the CO(2) laser, could be achieved with repetitive Er:YAG laser exposures.

Study design/materials and methods: Skin on the back of a Sprague-Dawley rat in vivo was irradiated with sequences of 1-10 Er:YAG laser pulses at a repetition rate of 10 or 33 Hz and single-pulse fluences from 0.8 to 1.4 J/cm(2). The resulting lesions were biopsied within 1 hour after laser exposure, and the histologic sections were examined by using optical microscopy.

Results: The depth of dermal collagen denaturation increases dramatically when 3-10 low-fluence Er:YAG laser pulses are stacked at a repetition rate of 10 or 33 Hz.

Conclusion: Coagulation of dermal collagen deeper than 200 microm below the epidermal-dermal junction is feasible by using the appropriate settings of a repetitive Er:YAG laser.

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