Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2000 Mar;14(2):89-92.
doi: 10.1002/(sici)1099-1573(200003)14:2<89::aid-ptr569>3.0.co;2-c.

Antiviral effect of flavonoids on the dengue virus

I Sánchez  1 , F Gómez-Garibay, J Taboada, B H Ruiz
Affiliations

Antiviral effect of flavonoids on the dengue virus

I Sánchez et al. Phytother Res. 2000 Mar.

Abstract

In the present study we analysed the possible antiviral effect on dengue viruses of different flavonoids extracted and identified at the Chemistry Institute, UNAM, from the Mexican plants Tephrosia madrensis, Tephrosia viridiflora and Tephrosia crassifolia. The flavonoids glabranine and 7-O-methyl-glabranine presented 70% inhibition on the dengue virus at a concentration of 25 microM, while methyl-hildgardtol A, hildgardtol A and elongatine had no effect on viral growth. Our results show that glabranine and 7-O-methyl-glabranine isolated from Tephrosia s.p. exert a dose-dependent inhibitory effect in vitro on the dengue virus.

PubMed Disclaimer

LinkOut - more resources