doi: 10.1002/(sici)1099-1573(200003)14:2<99::aid-ptr600>3.0.co;2-4.
Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats
Affiliations
- PMID: 10685105
- DOI: 10.1002/(sici)1099-1573(200003)14:2<99::aid-ptr600>3.0.co;2-4
Item in Clipboard
Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats
Phytother Res.
2000 Mar.
Abstract
The hydro-alcohol extract of the dry leaves of Peumus boldus and boldine, showed abortive and teratogenic action and changes in the blood levels of bilirubin, cholesterol, glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and urea in rats. The long term administration of the extract and boldine did not cause histological modification during a period of 90 days.
Copyright 2000 John Wiley & Sons, Ltd.
Similar articles
-
The effect of the aqueous extract Peumus boldus on the proliferation of hepatocytes and liver function in rats submitted to expanded hepatectomy.Acta Cir Bras. 2016 Sep;31(9):608-614. doi: 10.1590/S0102-865020160090000006. Acta Cir Bras. 2016. PMID: 27737346
-
Variation of the alkaloid content of Peumus boldus (boldo).Fitoterapia. 2018 Jun;127:179-185. doi: 10.1016/j.fitote.2018.02.020. Epub 2018 Feb 14. Fitoterapia. 2018. PMID: 29454020
-
Peumus boldus (Boldo) Aqueous Extract Present Better Protective Effect than Boldine Against Manganese-Induced Toxicity in D. melanogaster.Neurochem Res. 2016 Oct;41(10):2699-2707. doi: 10.1007/s11064-016-1984-z. Epub 2016 Jun 27. Neurochem Res. 2016. PMID: 27350578
-
Boldine and its antioxidant or health-promoting properties.Chem Biol Interact. 2006 Jan 5;159(1):1-17. doi: 10.1016/j.cbi.2005.09.002. Epub 2005 Oct 10. Chem Biol Interact. 2006. PMID: 16221469 Review.
-
Boldo and boldine: an emerging case of natural drug development.Pharmacol Res. 1994 Jan-Feb;29(1):1-12. doi: 10.1016/1043-6618(94)80093-6. Pharmacol Res. 1994. PMID: 8202440 Review.
Cited by
-
Low-protein diet does not alter reproductive, biochemical, and hematological parameters in pregnant Wistar rats.Braz J Med Biol Res. 2018;51(6):e6602. doi: 10.1590/1414-431x20186602. Epub 2018 May 21. Braz J Med Biol Res. 2018. PMID: 29791594 Free PMC article.
-
Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease.Front Pharmacol. 2019 Apr 12;10:351. doi: 10.3389/fphar.2019.00351. eCollection 2019. Front Pharmacol. 2019. PMID: 31031622 Free PMC article. Review.
-
Brazilian adolescents' knowledge and beliefs about abortion methods: a school-based internet inquiry.BMC Womens Health. 2014 Feb 13;14:27. doi: 10.1186/1472-6874-14-27. BMC Womens Health. 2014. PMID: 24521075 Free PMC article.
-
A Complete Review of Mexican Plants with Teratogenic Effects.Plants (Basel). 2022 Jun 24;11(13):1675. doi: 10.3390/plants11131675. Plants (Basel). 2022. PMID: 35807626 Free PMC article. Review.
-
Pharmacology of boldine: summary of the field and update on recent advances.Front Pharmacol. 2024 Sep 13;15:1427147. doi: 10.3389/fphar.2024.1427147. eCollection 2024. Front Pharmacol. 2024. PMID: 39346563 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
