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Meta-Analysis
. 2000 Feb;73(2):330-3.
doi: 10.1016/s0015-0282(99)00498-7.

Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis

M D Hornstein  1 , O K Davis, J B Massey, R J Paulson, J A Collins
Affiliations
Free article
Meta-Analysis

Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis

M D Hornstein et al. Fertil Steril. 2000 Feb.
Free article

Abstract

Objective: To evaluate whether the presence of antiphospholipid antibodies among women undergoing IVF affects the likelihood of IVF success.

Design: A meta-analysis of seven eligible studies on antiphospholipid antibodies and IVF outcome.

Main outcome measure(s): Odds ratios (ORs) and 95% confidence intervals (CIs) of an association between the presence of antiphospholipid antibodies and both clinical pregnancy and live birth from IVF.

Result(s): There was no significant association between antiphospholipid abnormalities and either clinical pregnancy (OR 0.99; 95% CI 0.64-1.53) or live birth (OR 1.07; 95% CI 0.66-1.75) in IVF patients.

Conclusion(s): The measurement of antiphospholipid antibodies is not warranted in patients undergoing IVF.

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