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Case Reports
. 2000 Mar;82(3):236-7.
doi: 10.1136/adc.82.3.236.

Fits, pyridoxine, and hyperprolinaemia type II

V Walker  1 , G A Mills, S A Peters, W L Merton
Affiliations
Case Reports

Fits, pyridoxine, and hyperprolinaemia type II

V Walker et al. Arch Dis Child. 2000 Mar.

Abstract

The rare inherited disorder hyperprolinaemia type II presents with fits in childhood, usually precipitated by infection. A diagnosis of hyperprolinaemia type II and vitamin B(6) deficiency was made in a well nourished child with fits. It is thought that pyridoxine deficiency was implicated in her fits and was the result of inactivation of the vitamin by the proline metabolite, pyrroline-5-carboxylate.

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References

    1. Am J Dis Child. 1967 Jan;113(1):77-80 - PubMed
    1. Arch Dis Child. 1989 Dec;64(12):1699-707 - PubMed
    1. Electroencephalogr Clin Neurophysiol. 1991 Mar;78(3):215-21 - PubMed
    1. Hum Mol Genet. 1998 Sep;7(9):1411-5 - PubMed

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