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. 2000 Mar 1;184(1):79-83.
doi: 10.1111/j.1574-6968.2000.tb08994.x.

Clonal turnover of enterohemorrhagic Escherichia coli O157:H7 in experimentally infected cattle

M Akiba  1 , T Sameshima, M Nakazawa
Affiliations

Clonal turnover of enterohemorrhagic Escherichia coli O157:H7 in experimentally infected cattle

M Akiba et al. FEMS Microbiol Lett. .

Abstract

A total of 401 enterohemorrhagic Escherichia coli (EHEC) O157:H7 isolates from two experimentally infected calves were analyzed using molecular biological methods. Genetic differences detected by pulsed-field gel electrophoresis were observed between the inoculated and recovered strains as early as 1 day post inoculation. The loss of the inoculated clone was observed in one calf. Replication and dissemination of the EHEC O157:H7 strains that mutated in cattle may result in the diversification of this organism among cattle populations.

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