Comment on

• Localization of the G protein betagamma complex in living cells during chemotaxis.

  Jin T, Zhang N, Long Y, Parent CA, Devreotes PN. Jin T, et al. Science. 2000 Feb 11;287(5455):1034-6. doi: 10.1126/science.287.5455.1034. Science. 2000. PMID: 10669414
• Polarization of chemoattractant receptor signaling during neutrophil chemotaxis.

  Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Bourne HR. Servant G, et al. Science. 2000 Feb 11;287(5455):1037-40. doi: 10.1126/science.287.5455.1037. Science. 2000. PMID: 10669415 Free PMC article.
• Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration.

  Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi PS, Suzuki A, Penninger JM. Sasaki T, et al. Science. 2000 Feb 11;287(5455):1040-6. doi: 10.1126/science.287.5455.1040. Science. 2000. PMID: 10669416
• Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction.

  Li Z, Jiang H, Xie W, Zhang Z, Smrcka AV, Wu D. Li Z, et al. Science. 2000 Feb 11;287(5455):1046-9. doi: 10.1126/science.287.5455.1046. Science. 2000. PMID: 10669417
• Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

  Hirsch E, Katanaev VL, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, Wymann MP. Hirsch E, et al. Science. 2000 Feb 11;287(5455):1049-53. doi: 10.1126/science.287.5455.1049. Science. 2000. PMID: 10669418