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. 2000 Feb;108(2):272-4.
doi: 10.1046/j.1365-2141.2000.01877.x.

Prevalence of the post-thrombotic syndrome in young women with previous venous thromboembolism

M D McColl  1 , J Ellison, I A Greer, R C Tait, I D Walker
Affiliations

Prevalence of the post-thrombotic syndrome in young women with previous venous thromboembolism

M D McColl et al. Br J Haematol. 2000 Feb.

Abstract

The prevalence of mild, moderate and severe post-thrombotic syndrome (PTS) among 43 young women with a previous single episode of deep vein thrombosis (DVT) was 67%, 7% and 0% respectively. Subjects were assessed at a mean 51 months after the event. Moderate PTS was more common in women with recurrent (n = 9) DVT (44%, P < 0.001). Chronic venous insufficiency, assessed by light reflection rheography (LRR), was significantly (P < 0.05) more prevalent in women with single previous DVT (n = 40), recurrent DVT (n = 9) and isolated pulmonary embolism (PE) (n = 19) compared with healthy age-matched controls (odds ratios 10.9, 52.4 and 3.8 respectively). LRR findings correlated with moderate, but not mild, PTS. There was no correlation between development of PTS and body mass index.

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