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. 1976:39:63-5.

Motilin effects on gastrointestinal motility and lower esophageal sphincter (LES) pressure in dogs

H M Jennewein, R Bauer, H Hummelt, G Lepsin, R Siewert, F Waldeck
  • PMID: 1069365

Motilin effects on gastrointestinal motility and lower esophageal sphincter (LES) pressure in dogs

H M Jennewein et al. Scand J Gastroenterol Suppl. 1976.

Abstract

Natural porcine motilin induces phasic contractions of the lower esophageal sphincter in dogs. These contractions are related to gastric contractions, which have the characteristics of interdigestive-motility patterns. Duodenal alkalinization produces an insignificant LES pressure increase after 5 minutes. No effect of motilin was observed when using isolated canine muscle strips.

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