Medical management of HIV disease in children
- PMID: 10697645
- PMCID: PMC7111615
- DOI: 10.1016/s0031-3955(05)70198-x
Medical management of HIV disease in children
Abstract
Significant advances have been made in the understanding of the pathophysiology of HIV infection since the beginning of the epidemic. This knowledge has translated into the development of new therapies for HIV and opportunistic infections, laboratory advances in monitoring viral and immune status, and a better understanding of factors affecting patient outcome. Concomitantly, significant progress has been made in the medical management of children with HIV infection in the past 5 years. The number of children reported with AIDS in the United States is decreasing, and efforts are shifting from caring for children with advanced immunosuppression and severe opportunistic infections to early HAART, maintenance of the immune system, and prevention of opportunistic infections. Primary care physicians are now more involved and informed in the care of HIV-infected patients. Although published data are limited, physicians who have been working with this population have observed a dramatic improvement in the quality of life and length of survival of these patients. Unfortunately, this progress is not shared by developing countries where resources are minimal and antiretroviral agents are commonly unavailable. Although efforts to develop a vaccine to prevent HIV infection are ongoing, progress has been slow. Education and awareness continue to be the most powerful weapons against HIV.
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References
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- Abitol C., Strauss J., Zilleruelo G. Validity of random urines to quantitate proteinuria in children with HIV nephropathy. Pediatr Nephrol. 1996;10:598. - PubMed
-
- American Academy of Pediatrics, Committee on Pediatric AIDS Evaluation and medical management of HIV-exposed infants. Pediatrics. 1997;99:909. - PubMed
-
- American Academy of Pediatrics, Committee on Pediatric AIDS Disclosure of illness status to Children and Adolescents with HIV infection. Pediatrics. 1999;103:164. - PubMed
-
- Anderson D.W., Virmani R., Reilly J.M. Prevalence of myocarditis at necropsy in the acquired immunodeficiency syndrome. J Am Coll Cardiol. 1988;11:792. - PubMed
-
- Andiman W., Shearer W. Lymphoid interstitial pneumonitis. In: Pizzo P., Wilfert C., editors. Pediatric AIDS: The Challenge of HIV Infection in Infants, Children and Adolescents. ed 3. Williams & Wilkins; Philadelphia, Lippincott: 1998. pp. 323–334.
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