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Case Reports
. 2000 Mar;38(3):1235-7.
doi: 10.1128/JCM.38.3.1235-1237.2000.

Molecular identification and epidemiological tracing of Pasteurella multocida meningitis in a baby

P Boerlin  1 , H H Siegrist, A P Burnens, P Kuhnert, P Mendez, G Prétat, R Lienhard, J Nicolet
Affiliations
Case Reports

Molecular identification and epidemiological tracing of Pasteurella multocida meningitis in a baby

P Boerlin et al. J Clin Microbiol. 2000 Mar.

Abstract

We report a case of Pasteurella multocida meningitis in a 1-month-old baby exposed to close contact with two dogs and a cat but without any known history of injury by these animals. 16S rRNA gene sequencing of the isolate from the baby allowed identification at the subspecies level and pointed to the cat as a possible source of infection. Molecular typing of Pasteurella isolates from the animals, from the baby, and from unrelated animals clearly confirmed that the cat harbored the same P. multocida subsp. septica strain on its tonsils as the one isolated from the cerebrospinal fluid of the baby. This case stresses the necessity of informing susceptible hosts at risk of contracting zoonotic agents about some basic hygiene rules when keeping pets. In addition, this study illustrates the usefulness of molecular methods for identification and epidemiological tracing of Pasteurella isolates.

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Figures

FIG. 1
FIG. 1
Macrorestriction analysis of P. multocida subsp. septica isolates. (A) Macrorestriction profiles of Pasteurella isolates obtained after digestion with SalI. Lanes: 1 to 9, P. multocida subsp. septica isolates from unrelated cats; 10 and 11, P. multocida subsp. septica isolates from the baby and from the contact cat, respectively. (B) Macrorestriction profiles of Pasteurella isolates obtained after digestion with SmaI. Isolates are in the same order as in panel A. The DNA in lane 1, isolate remained uncut because of methylation.
See this image and copyright information in PMC

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