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Comparative Study
. 2000 Mar;38(3):1247-9.
doi: 10.1128/JCM.38.3.1247-1249.2000.

Use of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

L L Jagodzinski  1 , D L Wiggins, J L McManis, S Emery, J Overbaugh, M Robb, S Bodrug, N L Michael
Affiliations
Comparative Study

Use of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

L L Jagodzinski et al. J Clin Microbiol. 2000 Mar.

Abstract

Optimal management of human immunodeficiency virus type 1 (HIV-1) disease requires accurate quantitation of viral RNA concentrations in plasma. Evidence for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitative viral RNA tests are described, for the first time, with calibrated viral isolates of diverse subtypes.

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