Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000 Mar 15;59(6):706-11.
doi: 10.1002/(SICI)1097-4547(20000315)59:6<706::AID-JNR2>3.0.CO;2-D.

Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease

J M Bronstein  1 , S Tiwari-Woodruff, A G Buznikov, D B Stevens
Affiliations
Review

Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease

J M Bronstein et al. J Neurosci Res. .

Abstract

Oligodendrocyte-specific protein (OSP/claudin-11) is a four transmembrane protein concentrated in central nervous system myelin. Recent evidence has emerged suggesting that OSP/claudin-11 is involved in membrane interactions at tight junctions and with the extracellular matrix. OSP/claudin-11 seems to modulate proliferation and migration of oligodendrocytes presumably through these interactions. Furthermore, evidence is presented implicating OSP/claudin-11 as an autoantigen in the development of autoimmune demyelinating disease.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources