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. 2000 Mar;8(3):120-8.
doi: 10.1016/s0966-842x(00)01705-4.

Phages will out: strategies of host cell lysis

I Young  1 , I Wang, W D Roof
Affiliations

Phages will out: strategies of host cell lysis

I Young et al. Trends Microbiol. 2000 Mar.

Abstract

Most phages accomplish host lysis using a muralytic enzyme, or endolysin, and a holin, which permeabilizes the membrane at a programmed time and thus controls the length of the vegetative cycle. By contrast, lytic single-stranded RNA and DNA phages accomplish lysis by producing a single lysis protein without muralytic activity.

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