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. 2000 Mar;2(3):E39-41.
doi: 10.1038/35004065.

The ins and outs of cell-polarity decisions

The ins and outs of cell-polarity decisions

E K O'Shea et al. Nat Cell Biol. 2000 Mar.

Abstract

The guanine-nucleotide-exchange factor Cdc24 is a critical regulator of cell polarity. Far1 is a key player in Cdc24 regulation, controlling Cdc24 activity in budding yeast by regulating its subcellular localization in response to two very different signals - one external and one internal.

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