p53: only ARF the story
- PMID: 10707099
- DOI: 10.1038/35004078
p53: only ARF the story
Abstract
Two tumour-suppressor proteins - p16INK4A and p19 ARF - encoded by the same genetic locus both have a role in arresting the cell-division cycle. New results have revealed further complexities in the pathways involved.
Comment on
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p16INK4A and p19ARF act in overlapping pathways in cellular immortalization.Nat Cell Biol. 2000 Mar;2(3):148-55. doi: 10.1038/35004020. Nat Cell Biol. 2000. PMID: 10707085
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