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Review
. 2000 Mar;7(3):R57-61.
doi: 10.1016/s1074-5521(00)00093-4.

Tyrosine sulfation: a modulator of extracellular protein-protein interactions

J W Kehoe  1 , C R Bertozzi
Affiliations
Review

Tyrosine sulfation: a modulator of extracellular protein-protein interactions

J W Kehoe et al. Chem Biol. 2000 Mar.

Abstract

Tyrosine sulfation is a post-translational modification of many secreted and membrane-bound proteins. Its biological roles have been unclear. Recent work has implicated tyrosine sulfate as a determinant of protein-protein interactions involved in leukocyte adhesion, hemostasis and chemokine signaling.

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