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Review
. 2000 Apr;12(2):166-72.
doi: 10.1016/s0952-7915(99)00067-9.

Notch signaling in T cell development

M L Deftos  1 , M J Bevan
Affiliations
Review

Notch signaling in T cell development

M L Deftos et al. Curr Opin Immunol. 2000 Apr.

Abstract

Notch signaling regulates cell fate decisions during development. Recent experiments suggest that Notch signaling is essential for initial commitment to the T cell lineage and may function together with signals from the pre-TCR and the TCR to regulate subsequent steps of T cell development.

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