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Clinical Trial
. 2000;72(2):46-8.

[Systemic enzyme therapy in chronic glomerulonephritis]

[Article in Russian]
O V Siniachenko, V N Kovalenko, I V Mukhin, G A Ignatenko, A I Terzov
  • PMID: 10717926
Clinical Trial

[Systemic enzyme therapy in chronic glomerulonephritis]

[Article in Russian]
O V Siniachenko et al. Ter Arkh. 2000.

Abstract

Aim: To try polyenzyme drug vobenzim in chronic glomerulonephritis (CGN).

Materials and methods: 174 CGN patients were randomized into 2 groups. The study group of 39 patients received conventional pathogenetic treatment plus vobenzim (initial dose 18-24, maintenance 12-15 dragees a day). Control group of 135 patients were given only pathogenetic therapy. 67 patients appeared ineligible.

Results: 3-6 months after the treatment the response was seen in 61.5% patients of the study and 17.8% patients of the control group. Side effects of vobenzim in CGN treatment were absent.

Conclusion: Enzyme therapy with vobenzim in CGN is safe and effective.

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