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. 2000 Mar;69(3):199-205.
doi: 10.1016/s0378-8741(99)00010-0.

In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts

F Benencia  1 , M C Courrèges, F C Coulombié
Affiliations

In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts

F Benencia et al. J Ethnopharmacol. 2000 Mar.

Abstract

The effects of Trichilia glabra (Meliaceae) aqueous leaf extract on mouse lymphocytes were studied. The in vitro proliferation of T and B lymphocytes was completely impaired. Besides, the extract significantly diminished both antibody and delayed hypersensitivity responses in treated mice. These results suggest that the extract exerts a marked immunomodulatory effect on the murine immune system.

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