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Review
. 2000 Apr;83(4):481-90.
doi: 10.1136/heart.83.4.481.

Intervention in coronary artery disease

S Windecker  1 , B Meier
Affiliations
Review

Intervention in coronary artery disease

S Windecker et al. Heart. 2000 Apr.
No abstract available

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Figures

Figure 1:
Figure 1:
Development of cardiac interventions during the 1990s in Europe. Data are obtained from the coronary circulation working group of the European Society of Cardiology and represent more than 30 European countries with a population > 500 million people. Note the steady increase in the number of PTCAs, coronary stent, and CABG procedures, in contrast to new devices.
Figure 2:
Figure 2:
Schematic diagram of the primary mechanisms of balloon angioplasty and coronary artery stenting.
Figure 3:
Figure 3:
Flow diagram illustrating the concept of provisional stenting with random patient numbers. The use of coronary artery stents on a provisional basis is associated with an excellent long term outcome and a low restenosis rate at minimised cost.
Figure 4:
Figure 4:
Serial changes in mean (SD) minimal luminal diameter of 72 lesions (blue circles) for which sequential studies over a three year period were completed, compared with a reference diameter (red circles). Note the significant improvement in mean minimal luminal diameter during the period from one year to three years after implantation of the stent; p < 0.001 for the comparison between the points linked by brackets. Reproduced from Kimura T et al15 with permission of the Massachusetts Medical Society.
Figure 5:
Figure 5:
Summary of results of four randomised coronary artery stent thromboprophylaxis trials. Dual antiplatelet treatment with aspirin and ticlopidine was superior to oral anticoagulation and aspirin treatment in the prevention of major adverse cardiac events in all trials. In the STARS trial dual antiplatelet treatment was superior to aspirin alone.
Figure 6:
Figure 6:
Odds ratio and confidence interval (CI) concerning death, MI, or additional coronary revascularisation at 30 days with glycoprotein IIb/IIIa receptor antagonists compared with placebo. Reproduced with permission from Meier B. Balloon angioplasty. In: Topol EJ, ed. Comprehensive cardiovascular medicine. Philadelphia: Lippincott-Raven, 1998:2251-84.
Figure 7:
Figure 7:
(A) Risk ratio and 95% confidence intervals for death or MI after CABG or PTCA for multivessel CAD at one, three, and five years in six randomised trials. (B) Risk ratio and 95% confidence intervals for reintervention after an initial strategy of CABG or PTCA for multivessel CAD at one year of follow up in six randomised trials. Reproduced with permission from Meier B. Balloon angioplasty. In: Topol EJ, ed. Comprehensive cardiovascular medicine. Philadelphia: Lippincott-Raven, 1998:2251-84.
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