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. 2000 Mar 15;72(3-4):207-16.
doi: 10.1016/s0378-1135(99)00206-0.

Detection of Borna disease virus in a pregnant mare and her fetus

K Hagiwara  1 , W Kamitani, S Takamura, H Taniyama, T Nakaya, H Tanaka, R Kirisawa, H Iwai, K Ikuta
Affiliations

Detection of Borna disease virus in a pregnant mare and her fetus

K Hagiwara et al. Vet Microbiol. .

Abstract

A pregnant mare showing pyrexia, reduced appetite, ataxia and paresis was euthanized and examined for the presence of Borna disease virus (BDV). Her brain, showing multiple neuronal degeneration and necrosis with hemorrhage, and the histologically normal brain of the fetus were both positive for BDV RNA. The BDV nucleotide sequences were identical in the mare and fetus in the second open reading frame (ORF). This is the first report of the possible vertical transmission of BDV in a horse.

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