Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2000 Mar 20;10(6):597-600.
doi: 10.1016/s0960-894x(00)00055-x.

Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine

R J Young  1 , R M Beams, K Carter, H A Clark, D M Coe, C L Chambers, P I Davies, J Dawson, M J Drysdale, K W Franzman, C French, S T Hodgson, H F Hodson, S Kleanthous, P Rider, D Sanders, D A Sawyer, K J Scott, B G Shearer, R Stocker, S Smith, M C Tackley, R G Knowles
Affiliations

Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine

R J Young et al. Bioorg Med Chem Lett. .

Abstract

The synthesis and in vitro evaluation of the acetamidine derivatives of hetero-substituted lysine and homolysine analogues have identified potent inhibitors of human nitric oxide synthase enzymes, including examples with marked selectivity for the inducible isoform.

PubMed Disclaimer

MeSH terms

LinkOut - more resources