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Review
. 2000 Feb;2(2):213-21.
doi: 10.1016/s1286-4579(00)00267-7.

Turning a corner on HIV neutralization?

J H Nunberg  1 , K E Follis, M Trahey, R A LaCasse
Affiliations
Free article
Review

Turning a corner on HIV neutralization?

J H Nunberg et al. Microbes Infect. 2000 Feb.
Free article

Abstract

HIV vaccine development has been hampered by the inability of conventional immunogens to elicit antibodies capable of neutralizing primary isolates of the virus. Recent studies using 'fusion-competent' immunogens that capture transitional intermediate structures of the functioning envelope protein suggest that this goal may now be achievable.

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