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. 2000 Apr;105(7):837-9.
doi: 10.1172/JCI9761.

Replication-selective microbiological agents: fighting cancer with targeted germ warfare

D H Kirn  1
Affiliations

Replication-selective microbiological agents: fighting cancer with targeted germ warfare

D H Kirn. J Clin Invest. 2000 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Electron micrograph of a squamous carcinoma cell from a patient following intratumoral injection with ONYX-015. This engineered strain of adenovirus replicates selectively in tumor cells and causes tumor-specific cytotoxicity. The higher magnification image, shown at the right, demonstrates that adenovirus particles form large arrays within the nucleus of infected tumor cells.
See this image and copyright information in PMC

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