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Review
. 2000 Apr;105(7):847-51.
doi: 10.1172/JCI9762.

Replication-selective adenoviruses as oncolytic agents

C Heise  1 , D H Kirn
Affiliations
Review

Replication-selective adenoviruses as oncolytic agents

C Heise et al. J Clin Invest. 2000 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Structure of human adenovirus, indicating the arrangement of capsid proteins. Fiber and penton recognize cellular receptors that mediate endocytosis of the virus.
Figure 2
Figure 2
Selective killing of cancer cells with a replication-selective agent. Viral agents can be engineered to replicate in and to kill tumor cells specifically, leaving healthy cells unharmed. Several strategies are available for designing such agents.
See this image and copyright information in PMC

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