Review
doi: 10.1097/00041433-200002000-00004.
The value of apolipoprotein E knockout mice for studying the effects of dietary fat and cholesterol on atherogenesis
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- PMID: 10750690
- DOI: 10.1097/00041433-200002000-00004
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Review
The value of apolipoprotein E knockout mice for studying the effects of dietary fat and cholesterol on atherogenesis
Curr Opin Lipidol.
2000 Feb.
Abstract
The ability of the apolipoprotein E-deficient mouse to develop spontaneous atherosclerosis, which resembles the human process, is an excellent model in which to assess the impact of dietary factors. This review discusses the role of several nutrients in the development of atherosclerosis and the mechanisms through which they act.
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