Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2000 Feb;10(1):53-9.
doi: 10.1054/ghir.2000.0140.

Diabetic retinopathy is associated with decreased serum levels of free IGF-I and changes of IGF-binding proteins

B Feldmann  1 , P M Jehle, S Mohan, G E Lang, G K Lang, J Brueckel, B O Boehm
Affiliations
Comparative Study

Diabetic retinopathy is associated with decreased serum levels of free IGF-I and changes of IGF-binding proteins

B Feldmann et al. Growth Horm IGF Res. 2000 Feb.

Abstract

In patients with diabetic retinopathy, elevated serum levels of total circulating insulin-like growth factor-I (IGF-I) have been implicated as an important mediator of the disease. There is no study, however, measuring free IGF-I levels in patients with diabetic retinopathy which mediate the biological effects of IGF-I and are modulated by a complex system of six specific IGF binding proteins (IGFBPs) and several IGFBP proteases.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources