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Review
. 2000 Apr;10(2):204-10.
doi: 10.1016/s0959-437x(00)00058-7.

The HP1 protein family: getting a grip on chromatin

J C Eissenberg  1 , S C Elgin
Affiliations
Review

The HP1 protein family: getting a grip on chromatin

J C Eissenberg et al. Curr Opin Genet Dev. 2000 Apr.

Abstract

HP1 was first described in Drosophila as a heterochromatin-associated protein with dosage-dependent effects on heterochromatin-induced gene silencing. Recently, membership of the HP1 protein family has expanded tremendously. A number of intriguing interactions between HP1 and other proteins have been described, implicating HP1 in gene regulation, DNA replication, and nuclear architecture.

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