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Review
. 2000 May-Jun;11(4):123-8.
doi: 10.1016/s1043-2760(00)00238-1.

Thyroid hormone action and brain development

N Koibuchi  1 , W W Chin
Affiliations
Review

Thyroid hormone action and brain development

N Koibuchi et al. Trends Endocrinol Metab. 2000 May-Jun.

Abstract

Thyroid hormone (TH) plays a crucial role in brain development. Developing rodent cerebellum might be an excellent model for studying the molecular mechanisms of TH action in the brain because perinatal hypothyroidism greatly affects its ontogeny. Although the TH-regulated genes that play crucial roles in cerebellar development have not yet been fully characterized, recent studies have provided novel insights into TH action in brain development.

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