Replication fork arrest and DNA recombination
- PMID: 10754549
- DOI: 10.1016/s0968-0004(00)01560-7
Replication fork arrest and DNA recombination
Abstract
Replication arrests are associated with genome rearrangements, which result from either homologous or non-homologous recombination. Interestingly, proteins involved in homologous recombination are able to convert an arrested replication fork into a recombination intermediate, which promotes replication restart and thus presumably prevents genome rearrangements.
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