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. 1997 Mar-Apr;64(2):215-9.
doi: 10.1007/BF02752450.

Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major

C Vergin  1 , N Kutukculer, N Cetingul, G Nisli, S Caglayan, S Oztop
Affiliations

Serum immunoglobulins, IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia major

C Vergin et al. Indian J Pediatr. 1997 Mar-Apr.

Abstract

Serum IgG, IgM, IgA, IgG subclasses (IgG1, G2, G3, G4), isohemagglutinins and complement-3 concentrations were measured in 23 beta-thalassemic patients suffering from recurrent infections. No significant abnormalities were found in these humoral immunity investigations, both in splenectomized and non-splenectomized patients. On the other hand, iron overload or repeated blood transfusions were not found to down-regulate the humoral immune system of thalassemic patients.

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