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. 2000 May-Jun;10(3):221-8.
doi: 10.1159/000016060.

Remote effects of acute ischemic stroke: A xenon CT cerebral blood flow study

G Rubin  1 , E I Levy, A M Scarrow, A D Firlik, A Karakus, L Wechsler, C A Jungreis, H Yonas
Affiliations

Remote effects of acute ischemic stroke: A xenon CT cerebral blood flow study

G Rubin et al. Cerebrovasc Dis. 2000 May-Jun.

Abstract

Objective: The purpose of this study was to verify transhemispheric diaschisis in the early hours after an ischemic event.

Methods: XeCT cerebral blood flow (CBF) studies within 8 h of stroke were studied in 23 patients. Mean CBF was evaluated in the ischemic area, contralateral hemisphere and ipsilateral cerebellum.

Results: A severe CBF reduction was found in the ischemic area (mean 9 +/- 3 ml/100 g/min). The mean CBF in the unaffected hemisphere (33 +/- 10 ml/100 g/min) was 35% less compared to the normal mean value. CBF was decreased in the cerebellum ipsilateral to the stroke (mean 31 +/- 12 ml/100 g/min) suggesting a blood flow depression of the whole brain.

Conclusions: During the initial hours of cerebral ischemia, the asymptomatic hemisphere demonstrated CBF depression that was part of the global flow reduction.

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