Chemokines in tissue-specific and microenvironment-specific lymphocyte homing
- PMID: 10781407
- DOI: 10.1016/s0952-7915(00)00096-0
Chemokines in tissue-specific and microenvironment-specific lymphocyte homing
Abstract
This review describes recent breakthroughs in our understanding of the roles played by chemokines in lymphocyte trafficking. These include the first demonstration that chemokines control lymphocyte/vascular recognition by shear-resistant rapid adhesion; the first example of specialized tissue-specific homing mediated by chemokines; and the implication that chemokines may control microenvironmental segregation within lymphoid organs.
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