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. 1975 Apr 1;121(7):991-4.
doi: 10.1016/0002-9378(75)90924-2.

Anosmia and hypogonadism with ovarian mosaicism

J R Jones, E Kemmann, J Cresci, G I Solish

Anosmia and hypogonadism with ovarian mosaicism

J R Jones et al. Am J Obstet Gynecol. .

Abstract

An 18-year-old woman with anosmia and hypogonadotropic hypogonadism is presented. In addition endocrinologic evaluation revealed an apparent deficiency in pituitary growth hormone secretion in response to hypoglycemia and an ovarian insensitivity to exogenous gonadotropins. The ovaries, which on histologic examination appeared to be normal, upon karyotyping showed a chromosomal mosaicism, probably 46, XX/47, XXF+.

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