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. 2000 May;38(5):1988-9.
doi: 10.1128/JCM.38.5.1988-1989.2000.

Evaluation of the MB/BacT mycobacterium detection system for susceptibility testing of Mycobacterium tuberculosis

M S Díaz-Infantes  1 , M J Ruiz-Serrano, L Martínez-Sánchez, A Ortega, E Bouza
Affiliations

Evaluation of the MB/BacT mycobacterium detection system for susceptibility testing of Mycobacterium tuberculosis

M S Díaz-Infantes et al. J Clin Microbiol. 2000 May.

Abstract

The MB/BacT mycobacterium detection system was evaluated for its performance in the susceptibility testing of Mycobacterium tuberculosis. Eighty-three M. tuberculosis isolates were processed. Results for all isoniazid-, rifampin- and streptomycin-susceptible, isoniazid-resistant, and rifampin-resistant M. tuberculosis isolates with the MB/BacT system agreed 100% with those obtained by the agar proportion method. The agreements between the two methods for streptomycin- and ethambutol-resistant isolates were 96.4 and 90.4%, respectively. The susceptibility test results were obtained in 7 days, on average. These data demonstrate that the MB/BacT system is an accurate, nonradiometric method for rapid susceptibility testing of M. tuberculosis.

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