Infective endocarditis complicated with progressive heart failure due to beta-lactamase-producing Cardiobacterium hominis
- PMID: 10790145
- PMCID: PMC86656
- DOI: 10.1128/JCM.38.5.2015-2017.2000
Infective endocarditis complicated with progressive heart failure due to beta-lactamase-producing Cardiobacterium hominis
Abstract
We describe a 66-year-old woman with infective endocarditis due to Cardiobacterium hominis whose condition, complicated by severe aortic regurgitation and congestive heart failure, necessitated aortic valve replacement despite treatment with ceftriaxone followed by ciprofloxacin. The blood isolate of C. hominis produced beta-lactamase and exhibited high-level resistance to penicillin (MIC, >==256 microgram/ml) and reduced susceptibility to vancomycin (MIC, 8 microgram/ml).
Figures
References
-
- Christin R D. Cardiobacterium hominis endocarditis in a patient with a hypersensitivity reaction to penicillin. Successful treatment with partial resection of the posterior mitral valve leaflet and antibiotic therapy with cefazolin. Infection. 1990;18:291–293. - PubMed
-
- Holmes B, Pickett M J, Hollis D G. Unusual gram-negative bacteria, including Capnocytophaga, Eikenella, Pasteurella, and Streptobacillus. In: Murray P R, Baron E J, Pfaller M A, Tenover F C, Yolken R H, editors. Manual of clinical microbiology. 6th ed. Washington, D.C.: American Society for Microbiology; 1995. pp. 499–503.
-
- Joklik W K, Willet H P, Amos D B, Wilfert C M, editors. Zinsser microbiology. 20th ed. Norwalk, Conn: Appleton & Lange; 1992. p. 605.
-
- Khizzi N E, Kasab S A, Osoba A O. HACEK group endocarditis at the Riyadh Armed Forces Hospital. J Infect. 1997;34:69–74. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
