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Review
. 2000 Apr 1;355(9210):1176-8.
doi: 10.1016/S0140-6736(00)02074-2.

The taxanes: an update

J Crown  1 , M O'Leary
Affiliations
Review

The taxanes: an update

J Crown et al. Lancet. .

Abstract

The taxanes are anticancer cytotoxics that stabilise cellular microtubules. Two members, paclitaxel and docetaxel have substantial activity. One or both agents are widely accepted as evidence-based components of therapy for advanced breast, lung, and ovarian carcinomas. Paclitaxel has recently been approved in the USA for the adjuvant treatment of early stage node-positive breast carcinoma.

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Comment in

  • Taxanes as adjuvant for breast cancer.
    Goldhirsch A, Francis P, Castiglione-Gertsch M, Gelber RD, Coates AS. Goldhirsch A, et al. Lancet. 2000 Aug 5;356(9228):507-8. doi: 10.1016/S0140-6736(05)74177-5. Lancet. 2000. PMID: 10981914 No abstract available.

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