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Comment
. 2000 May;156(5):1485-8.
doi: 10.1016/S0002-9440(10)65019-5.

Heme oxygenase-1 in tissue pathology: the Yin and Yang

Z Dong  1 , Y Lavrovsky, M A Venkatachalam, A K Roy
Affiliations
Comment

Heme oxygenase-1 in tissue pathology: the Yin and Yang

Z Dong et al. Am J Pathol. 2000 May.
No abstract available

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Figures

Figure 1.
Figure 1.
Heme oxygenase catalyzes the degradation of heme, resulting in the production of biliverdin, carbon monoxide (CO), and free iron in the ferrous form (Fe2+). In the presence of biliverdin reductase, biliverdin is rapidly converted into bilirubin. The role played by heme oxygenase in tissue pathology is determined by a delicate balance between the injurious and protective actions of heme, bilirubin, CO, and Fe2+.
See this image and copyright information in PMC

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