Comparative Study
doi: 10.1093/nar/1.11.1497.
Rifampicin-resistant bacteriophage PBS2 infection and RNA polymerase in Bacillus subtilis
- PMID: 10793705
- PMCID: PMC343426
- DOI: 10.1093/nar/1.11.1497
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Comparative Study
Rifampicin-resistant bacteriophage PBS2 infection and RNA polymerase in Bacillus subtilis
Nucleic Acids Res.
1974 Nov.
Free PMC article
Abstract
Bacteriophage PBS2 replication is unaffected by rifampicin and other rifamycin derivatives, which are potent inhibitors of Bacillus subtilis RNA synthesis. Extracts of gently-lysed infected cells contain a DNA-dependent RNA polymerase activity which is specific for uracil-containing PBS2 DNA. The PBS2-induced RNA polymerase is insensitive to rifamycin derivatives which inhibit the host's RNA polymerase.
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