Glycosidase inhibitors and their chemotherapeutic value, Part 1
- PMID: 10798237
Glycosidase inhibitors and their chemotherapeutic value, Part 1
Abstract
The various compounds that have been investigated as glycosidase inhibitors are reviewed. The first of three parts of this review article covers the following classes of compounds: sugar, lactones and hydroximolactones, glycosyl halides, oligosaccharides, glycosides and their derivatives, deoxy thiosugar derivatives, thioglycosides, deoxy amino and guanidino sugars, glycosylamines, anhydrosugars and their analogues, deoxysugars, glycals, C-glycosides and C-nucleosides.
Similar articles
-
Glycosidase inhibitors and their chemotherapeutic value, Part 3.Pharmazie. 2000 Jun;55(6):403-15. Pharmazie. 2000. PMID: 10907246 Review.
-
Glycosidase inhibitors and their chemotherapeutic value, Part 2.Pharmazie. 2000 May;55(5):331-48. Pharmazie. 2000. PMID: 11828612 Review.
-
Functionalization of glycals leading to 2-deoxy-O-glycosides, aminosugars, nitrosugars and glycosidase inhibitors: our experience.Chimia (Aarau). 2012;66(12):905-12. doi: 10.2533/chimia.2012.905. Chimia (Aarau). 2012. PMID: 23394274 Review.
-
Synthesis and testing of 2-deoxy-2,2-dihaloglycosides as mechanism-based inhibitors of alpha-glycosidases.J Org Chem. 2008 Apr 18;73(8):3070-7. doi: 10.1021/jo702565q. Epub 2008 Mar 18. J Org Chem. 2008. PMID: 18345685
-
Glycosidase inhibitors as conformational transition state analogues.Chem Commun (Camb). 2007 Sep 28;(36):3747-9. doi: 10.1039/b705607a. Epub 2007 Jun 28. Chem Commun (Camb). 2007. PMID: 17851615
Cited by
-
A new synthetic access to 2-N-(glycosyl)thiosemicarbazides from 3-N-(glycosyl)oxadiazolinethiones and the regioselectivity of the glycosylation of their oxadiazolinethione precursors.Beilstein J Org Chem. 2013;9:135-46. doi: 10.3762/bjoc.9.16. Epub 2013 Jan 21. Beilstein J Org Chem. 2013. PMID: 23400104 Free PMC article.
-
Synthesis of a new class of aminocyclitol analogues with the conduramine D-2 configuration.Beilstein J Org Chem. 2010 Feb 15;6:15. doi: 10.3762/bjoc.6.15. Beilstein J Org Chem. 2010. PMID: 20485597 Free PMC article.
-
Double-headed nucleosides: Synthesis and applications.Beilstein J Org Chem. 2021 Jun 8;17:1392-1439. doi: 10.3762/bjoc.17.98. eCollection 2021. Beilstein J Org Chem. 2021. PMID: 34194579 Free PMC article. Review.