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Review
. 2000 May;6(5):513-9.
doi: 10.1038/74994.

Mitochondrial control of cell death

G Kroemer  1 , J C Reed
Affiliations
Review

Mitochondrial control of cell death

G Kroemer et al. Nat Med. 2000 May.

Abstract

In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.

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