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. 1975;288(2-3):323-7.
doi: 10.1007/BF00500538.

Quantal release parameters during fade of endplate potentials

D D Branisteanu, M D Miyamoto, R L Volle

Quantal release parameters during fade of endplate potentials

D D Branisteanu et al. Naunyn Schmiedebergs Arch Pharmacol. 1975.

Abstract

An analog of hemicholinium-3 caused the fade of endplate potentials during repetitive stimulation at low rates. The quantal parameters of release were estimated during steady-state conditions before and in the presence of the drug. The fade of EPP's was associated with a decrease in quantal content (m). The decrease in m was, in turn, associated with a decrease in the binomial parameter n and an increase in the binomial parameter p. The changes in n and p are discussed in relation to available stores of transmitter and the probability of transmitter release.

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References

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