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. 1975 Aug;8(3):437-41.
doi: 10.1099/00222615-8-3-437.

R-factor mediated beta-lactamase production by Haemophilus influenzae

R-factor mediated beta-lactamase production by Haemophilus influenzae

R B Sykes et al. J Med Microbiol. 1975 Aug.

Abstract

Production of beta-lactamase by 15 strains of Haemophilus influenzae has been investigated. All the strains produce a constitutive beta-lactamase, which readily hydrolyses penicillin G, ampicillin, and cephaloridine. The beta-lactamase produced by these strains is indistinguishable from the type-IIIa enzyme commonly found in strains of Escherichia coli. The beta-lactamase gene has been transferred from the enzyme-producing strains of Haemophilus to strains of H. parainfluenzae and a strain of E. coli.

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