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. 1975 Oct 11;4(5988):77-9.
doi: 10.1136/bmj.4.5988.77.

Trigger factors and HL-A antigens in chronic active hepatitis

J Lindberg, A Lindholm, P Lundin, S Iwarson

Trigger factors and HL-A antigens in chronic active hepatitis

J Lindberg et al. Br Med J. .

Abstract

Forty-six patients with histologically verified chronic active hepatitis (CAH) were divided into three groups according to whether the CAH was virus-induced, drug-induced, or cryptogenic. The frequency of the HL-A antigens 1 and 8 was increased in the cryptogenic group while the other groups did not differ significantly from healthy controls. Autoantibodies were often found in high titres in the drug-induced and cryptogenic groups but were infrequent in the virus-induced group.

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