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. 2000;102(401):27-38.

Fatty acids enhanced tubermycin production by Pseudomonas strain 2HS

K C Keudell  1 , J K Huang, L Wen, W E Klopfenstein, M O Bagby, A C Lanser, R D Plattner, R E Peterson, D Weisleder
Affiliations
  • PMID: 10817518

Fatty acids enhanced tubermycin production by Pseudomonas strain 2HS

K C Keudell et al. Microbios. 2000.

Abstract

A new microbial isolate, Pseudomonas 2HS, produced trace amounts of a greenish-yellow pigment when grown aerobically in a 1% yeast extract medium at 30 degrees C and shaken at 250 rpm for 5 days. In contrast, cells produced more greenish-yellow pigment (2.16 mg/15 ml culture) when grown in the presence of 0.5% 12-hydroxyoctadecanoic acid (w/v). The greenish-yellow pigment was identified as phenazine-1-carboxylic acid (tubermycin B), and the Pseudomonas 2HS was identified as P. aeruginosa 2HS. This is the first report that 12-hydroxyoctadecanoic, ricinoleic and other fatty acids can enhance the production of phenazine-1-carboxylic acid by a Pseudomonas species.

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